News and Views
Nature Medicine 15, 608 - 610 (2009)
doi:10.1038/nm0609-608
Tension in the vasculature
Andrew V Benest1 & Hellmut G Augustin1
- Andrew V. Benest and Hellmut G. Augustin are in the Joint Research Division Vascular Biology, Medical Faculty Mannheim, Heidelberg University (CBTM) and the German Cancer Research Center Heidelberg (DKFZ-ZMBH Alliance), Germany.
Correspondence to: Hellmut G Augustin1 e-mail: augustin@angiogenese.de
Abstract
Blood vessels arise from progenitor cells, grow and branch by sprouting from preexisting vessels and remodel by splitting longitudinally. A new study proposes an additional mechanism. It seems that vascularization can proceed through the mechanical translocation and expansion of existing vessels, which loop into vascularising tissue (pages 657–664).
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