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Nature Medicine 15, 491 - 493 (2009)
doi:10.1038/nm0509-491
Angiogenesis: escape from hypoxia
Mathew L Coleman1 & Peter J Ratcliffe1
- Mathew L. Coleman and Peter J. Ratcliffe are at the Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.
Correspondence to: Peter J Ratcliffe1 e-mail: pjr@well.ox.ac.uk
Abstract
Current attempts to block angiogenesis during cancer and other diseases are limited partly by their effects on normal angiogenic processes. Could a more targeted approach emerge from the identification of a factor required for pathological angiogenesis under conditions of hypoxia (pages 553–558)?
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