News and Views
Nature Medicine 15, 488 - 490 (2009)
doi:10.1038/nm0509-488
Breaking the gene barrier in schizophrenia
Szatmár Horváth2 & Károly Mirnics1
- Károly Mirnics is in the Department of Psychiatry, Vanderbilt University, Nashville, Tennessee, USA.
- Szatmár Horváth is in the Department of Psychiatry, Vanderbilt University, Nashville, Tennessee, USA, and the Department of Psychiatry, University of Szeged, Szeged, Hungary.
Correspondence to: Károly Mirnics1 e-mail: karoly.mirnics@vanderbilt.edu
Abstract
Studies of schizophrenia have been plagued by shortcomings such as weak genetic association with disease, inadequate animal models and limited replication of gene expression findings. Future success may lie not in overcoming any one of these limitations but in a broad approach strengthening the evidence in each area. Using such an approach, neuroscientists have uncovered a new gene behind the disease (pages 509–518).
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated.
RESEARCH
A primate-specific, brain isoform of KCNH2 affects cortical physiology, cognition, neuronal repolarization and risk of schizophreniaNature Medicine Article (01 May 2009)
