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Nature Medicine 15, 487 - 488 (2009)
doi:10.1038/nm0509-487
Blood pressure control: salt gets under your skin
Paul J Marvar1, Frank J Gordon1 & David G Harrison1
- Paul J. Marvar and David G. Harrison are in the Department of Medicine Division of Cardiology, and Frank J. Gordon is in the Department of Pharmacology, Emory University School of Medicine, Atlanta, Georgia, USA.
Correspondence to: David G Harrison1 e-mail: dharr02@emory.edu
Abstract
After an increase in dietary salt, the excess sodium is stored under the skin—stimulating lymphatic growth through the activity of macrophages (pages 545–552). The findings should recast thinking about how blood pressure is regulated.
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RESEARCH
Macrophages regulate salt-dependent volume and blood pressure by a vascular endothelial growth factor-C?dependent buffering mechanismNature Medicine Article (01 May 2009)
