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Nature Medicine 15, 249 - 250 (2009)
doi:10.1038/nm0309-249

When integrins fail to integrate

Andrés Hidalgo1 & Paul S Frenette1

  1. Andrés Hidalgo and Paul S. Frenette are at Mount Sinai School of Medicine, Departments of Medicine and Gene and Cell Medicine, Black Family Stem Cell Institute, Immunology Institute, 1 Gustave Levy Place, Box 1079, New York, New York 10029, USA. e-mail: paul.frenette@mssm.edu


Three studies implicate Kindlin-3, a molecule that mediates signaling through integrins, in a rare disorder characterized by spontaneous bleeding and susceptibility to infection (pages 300–305, 306–312 and 313–318).

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