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Nature Medicine 14, 812 - 813 (2008)
doi:10.1038/nm0808-812

Predicting the future for people with lung cancer

Yang Xie1 & John D Minna1

  1. Yang Xie and John D. Minna are in the Department of Clinical Sciences and Hamon Center for Therapeutic Oncology Research, University of Texas Southwestern Medical Center, 6000 Harry Hines Boulevard, Dallas, Texas 75390-8593, USA.
    e-mail: yang.xie@utsouthwestern.edu
    e-mail: john.minna@utsouthwestern.edu


A large multicenter study shows that lung adenocarcinomas have messenger RNA expression signatures that greatly add to the use of clinical data in predicting an individual's survival (pages 822–827).


A major goal of 'personalized' medicine for cancer is to develop the tools to sample a patient's tumor and then perform molecular analyses to identify the tumor type, its behavior in the patient, the patient's prognosis and the best treatment. The study by Shedden et al.1 in this issue of Nature Medicine provides an important step in this direction.

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