
TY  - JOUR
AU  - Selkoe, D.J.
TI  - Alzheimer's disease: genes, proteins, and therapy
JA  - Physiol. Rev.
PY  - 2001///
VL  - 81
SP  - 741
EP  - 766
PB  - Nature Publishing Group
ER  -

TY  - JOUR
AU  - Li, M.O.
AU  - Wan, Y.Y.
AU  - Sanjabi, S.
AU  - Robertson, A.K.
AU  - Flavell, R.A.
TI  - Transforming growth factor-[beta] regulation of immune responses
JA  - Annu. Rev. Immunol.
PY  - 2006///
VL  - 24
SP  - 99
EP  - 146
PB  - Nature Publishing Group
M3  - 10.1146/annurev.immunol.24.021605.090737
N1  - 10.1146/annurev.immunol.24.021605.090737
UR  - http://dx.doi.org/10.1146/annurev.immunol.24.021605.090737
ER  -

TY  - JOUR
AU  - Laouar, Y.
AU  - Sutterwala, F.S.
AU  - Gorelik, L.
AU  - Flavell, R.A.
TI  - Transforming growth factor-[beta] controls T helper type 1 cell development through regulation of natural killer cell interferon-gamma
JA  - Nat. Immunol.
PY  - 2005///
VL  - 6
SP  - 600
EP  - 607
PB  - Nature Publishing Group
M3  - 10.1038/ni1197
N1  - 10.1038/ni1197
UR  - http://dx.doi.org/10.1038/ni1197
ER  -

TY  - JOUR
AU  - Hsiao, K.
TI  - Correlative memory deficits, A[beta] elevation and amyloid plaques in transgenic mice
JA  - Science
PY  - 1996///
VL  - 274
SP  - 99
EP  - 102
PB  - Nature Publishing Group
M3  - 10.1126/science.274.5284.99
N1  - 10.1126/science.274.5284.99
UR  - http://dx.doi.org/10.1126/science.274.5284.99
ER  -

TY  - JOUR
AU  - Akiyama, H.
TI  - Inflammation and Alzheimer's disease
JA  - Neurobiol. Aging
PY  - 2000///
VL  - 21
SP  - 383
EP  - 421
PB  - Nature Publishing Group
M3  - 10.1016/S0197-4580(00)00124-X
N1  - 10.1016/S0197-4580(00)00124-X
UR  - http://dx.doi.org/10.1016/S0197-4580(00)00124-X
ER  -

TY  - JOUR
AU  - Wisniewski, H.M.
AU  - Wegiel, J.
AU  - Wang, K.C.
AU  - Kujawa, M.
AU  - Lach, B.
TI  - Ultrastructural studies of the cells forming amyloid fibers in classical plaques
JA  - Can. J. Neurol. Sci.
PY  - 1989///
VL  - 16
SP  - 535
EP  - 542
PB  - Nature Publishing Group
ER  -

TY  - JOUR
AU  - Brionne, T.C.
AU  - Tesseur, I.
AU  - Masliah, E.
AU  - Wyss-Coray, T.
TI  - Loss of TGF-[beta]1 leads to increased neuronal cell death and microgliosis in mouse brain
JA  - Neuron
PY  - 2003///
VL  - 40
SP  - 1133
EP  - 1145
PB  - Nature Publishing Group
M3  - 10.1016/S0896-6273(03)00766-9
N1  - 10.1016/S0896-6273(03)00766-9
UR  - http://dx.doi.org/10.1016/S0896-6273(03)00766-9
ER  -

TY  - JOUR
AU  - Wyss-Coray, T.
AU  - Lin, C.
AU  - Sanan, D.A.
AU  - Mucke, L.
AU  - Masliah, E.
TI  - Chronic overproduction of transforming growth factor-[beta]1 by astrocytes promotes Alzheimer's disease-like microvascular degeneration in transgenic mice
JA  - Am. J. Pathol.
PY  - 2000///
VL  - 156
SP  - 139
EP  - 150
PB  - Nature Publishing Group
ER  -

TY  - JOUR
AU  - Wyss-Coray, T.
TI  - Amyloidogenic role of cytokine TGF-[beta]1 in transgenic mice and in Alzheimer's disease
JA  - Nature
PY  - 1997///
VL  - 389
SP  - 603
EP  - 606
PB  - Nature Publishing Group
M3  - 10.1038/39321
N1  - 10.1038/39321
UR  - http://dx.doi.org/10.1038/39321
ER  -

TY  - JOUR
AU  - Wyss-Coray, T.
TI  - TGF-[beta]1 promotes microglial amyloid-[beta] clearance and reduces plaque burden in transgenic mice
JA  - Nat. Med.
PY  - 2001///
VL  - 7
SP  - 612
EP  - 618
PB  - Nature Publishing Group
M3  - 10.1038/87945
N1  - 10.1038/87945
UR  - http://dx.doi.org/10.1038/87945
ER  -

TY  - JOUR
AU  - Tesseur, I.
TI  - Deficiency in neuronal TGF-[beta] signaling promotes neurodegeneration and Alzheimer's pathology
JA  - J. Clin. Invest.
PY  - 2006///
VL  - 116
SP  - 3060
EP  - 3069
PB  - Nature Publishing Group
M3  - 10.1172/JCI27341
N1  - 10.1172/JCI27341
UR  - http://dx.doi.org/10.1172/JCI27341
ER  -

TY  - JOUR
AU  - Holcomb, L.
TI  - Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes
JA  - Nat. Med.
PY  - 1998///
VL  - 4
SP  - 97
EP  - 100
PB  - Nature Publishing Group
M3  - 10.1038/nm0198-097
N1  - 10.1038/nm0198-097
UR  - http://dx.doi.org/10.1038/nm0198-097
ER  -

TY  - JOUR
AU  - King, D.L.
TI  - Progressive and gender-dependent cognitive impairment in the APP(SW) transgenic mouse model for Alzheimer's disease
JA  - Behav. Brain Res.
PY  - 1999///
VL  - 103
SP  - 145
EP  - 162
PB  - Nature Publishing Group
M3  - 10.1016/S0166-4328(99)00037-6
N1  - 10.1016/S0166-4328(99)00037-6
UR  - http://dx.doi.org/10.1016/S0166-4328(99)00037-6
ER  -

TY  - JOUR
AU  - Irizarry, M.C.
AU  - McNamara, M.
AU  - Fedorchak, K.
AU  - Hsiao, K.
AU  - Hyman, B.T.
TI  - APPSw transgenic mice develop age-related A[beta] deposits and neuropil abnormalities, but no neuronal loss in CA1
JA  - J. Neuropathol. Exp. Neurol.
PY  - 1997///
VL  - 56
SP  - 965
EP  - 973
PB  - Nature Publishing Group
M3  - 10.1097/00005072-199709000-00002
N1  - 10.1097/00005072-199709000-00002
UR  - http://dx.doi.org/10.1097/00005072-199709000-00002
ER  -

TY  - JOUR
AU  - Callahan, M.J.
TI  - Augmented senile plaque load in aged female [beta]-amyloid precursor protein-transgenic mice
JA  - Am. J. Pathol.
PY  - 2001///
VL  - 158
SP  - 1173
EP  - 1177
PB  - Nature Publishing Group
ER  -

TY  - JOUR
AU  - Ellis, R.J.
TI  - Cerebral amyloid angiopathy in the brains of patients with Alzheimer's disease: the CERAD experience, Part XV
JA  - Neurology
PY  - 1996///
VL  - 46
SP  - 1592
EP  - 1596
PB  - Nature Publishing Group
ER  -

TY  - JOUR
AU  - Robbins, E.M.
TI  - Kinetics of cerebral amyloid angiopathy progression in a transgenic mouse model of Alzheimer disease
JA  - J. Neurosci.
PY  - 2006///
VL  - 26
SP  - 365
EP  - 371
PB  - Nature Publishing Group
M3  - 10.1523/JNEUROSCI.3854-05.2006
N1  - 10.1523/JNEUROSCI.3854-05.2006
UR  - http://dx.doi.org/10.1523/JNEUROSCI.3854-05.2006
ER  -

TY  - JOUR
AU  - DeMattos, R.B.
AU  - Bales, K.R.
AU  - Cummins, D.J.
AU  - Paul, S.M.
AU  - Holtzman, D.M.
TI  - Brain to plasma amyloid-[beta] efflux: a measure of brain amyloid burden in a mouse model of Alzheimer's disease
JA  - Science
PY  - 2002///
VL  - 295
SP  - 2264
EP  - 2267
PB  - Nature Publishing Group
M3  - 10.1126/science.1067568
N1  - 10.1126/science.1067568
UR  - http://dx.doi.org/10.1126/science.1067568
ER  -

TY  - JOUR
AU  - Lemere, C.A.
TI  - Nasal A[beta] treatment induces anti-A[beta] antibody production and decreases cerebral amyloid burden in PD-APP mice
JA  - Ann. NY Acad. Sci.
PY  - 2000///
VL  - 920
SP  - 328
EP  - 331
PB  - Nature Publishing Group
ER  -

TY  - JOUR
AU  - Jankowsky, J.L.
TI  - Co-expression of multiple transgenes in mouse CNS: a comparison of strategies
JA  - Biomol. Eng.
PY  - 2001///
VL  - 17
SP  - 157
EP  - 165
PB  - Nature Publishing Group
M3  - 10.1016/S1389-0344(01)00067-3
N1  - 10.1016/S1389-0344(01)00067-3
UR  - http://dx.doi.org/10.1016/S1389-0344(01)00067-3
ER  -

TY  - JOUR
AU  - Geissmann, F.
AU  - Jung, S.
AU  - Littman, D.R.
TI  - Blood monocytes consist of two principal subsets with distinct migratory properties
JA  - Immunity
PY  - 2003///
VL  - 19
SP  - 71
EP  - 82
PB  - Nature Publishing Group
M3  - 10.1016/S1074-7613(03)00174-2
N1  - 10.1016/S1074-7613(03)00174-2
UR  - http://dx.doi.org/10.1016/S1074-7613(03)00174-2
ER  -

TY  - JOUR
AU  - Westerman, M.A.
TI  - The relationship between A[beta] and memory in the Tg2576 mouse model of Alzheimer's disease
JA  - J. Neurosci.
PY  - 2002///
VL  - 22
SP  - 1858
EP  - 1867
PB  - Nature Publishing Group
ER  -

TY  - JOUR
AU  - Nicoll, J.A.
TI  - Neuropathology of human Alzheimer disease after immunization with amyloid-[beta] peptide: a case report
JA  - Nat. Med.
PY  - 2003///
VL  - 9
SP  - 448
EP  - 452
PB  - Nature Publishing Group
M3  - 10.1038/nm840
N1  - 10.1038/nm840
UR  - http://dx.doi.org/10.1038/nm840
ER  -

TY  - JOUR
AU  - Town, T.
AU  - Nikolic, V.
AU  - Tan, J.
TI  - The microglial [ldquo]activation[rdquo] continuum: from innate to adaptive responses
JA  - J. Neuroinflammation
PY  - 2005///
VL  - 2
SP  - 24
PB  - Nature Publishing Group
M3  - 10.1186/1742-2094-2-24
N1  - 10.1186/1742-2094-2-24
UR  - http://dx.doi.org/10.1186/1742-2094-2-24
ER  -

TY  - JOUR
AU  - Stalder, A.K.
TI  - Invasion of hematopoietic cells into the brain of amyloid precursor protein transgenic mice
JA  - J. Neurosci.
PY  - 2005///
VL  - 25
SP  - 11125
EP  - 11132
PB  - Nature Publishing Group
M3  - 10.1523/JNEUROSCI.2545-05.2005
N1  - 10.1523/JNEUROSCI.2545-05.2005
UR  - http://dx.doi.org/10.1523/JNEUROSCI.2545-05.2005
ER  -

TY  - JOUR
AU  - Simard, A.R.
AU  - Soulet, D.
AU  - Gowing, G.
AU  - Julien, J.P.
AU  - Rivest, S.
TI  - Bone marrow-derived microglia play a critical role in restricting senile plaque formation in Alzheimer's disease
JA  - Neuron
PY  - 2006///
VL  - 49
SP  - 489
EP  - 502
PB  - Nature Publishing Group
M3  - 10.1016/j.neuron.2006.01.022
N1  - 10.1016/j.neuron.2006.01.022
UR  - http://dx.doi.org/10.1016/j.neuron.2006.01.022
ER  -

TY  - JOUR
AU  - El Khoury, J.
TI  - Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like disease
JA  - Nat. Med.
PY  - 2007///
VL  - 13
SP  - 432
EP  - 438
PB  - Nature Publishing Group
M3  - 10.1038/nm1555
N1  - 10.1038/nm1555
UR  - http://dx.doi.org/10.1038/nm1555
ER  -

TY  - JOUR
AU  - Ajami, B.
AU  - Bennett, J.L.
AU  - Krieger, C.
AU  - Tetzlaff, W.
AU  - Rossi, F.M.
TI  - Local self-renewal can sustain CNS microglia maintenance and function throughout adult life
JA  - Nat. Neurosci.
PY  - 2007///
VL  - 10
SP  - 1538
EP  - 1543
PB  - Nature Publishing Group
M3  - 10.1038/nn2014
N1  - 10.1038/nn2014
UR  - http://dx.doi.org/10.1038/nn2014
ER  -

TY  - JOUR
AU  - Mildner, A.
TI  - Microglia in the adult brain arise from Ly-6ChiCCR2+ monocytes only under defined host conditions
JA  - Nat. Neurosci.
PY  - 2007///
VL  - 10
SP  - 1544
EP  - 1553
PB  - Nature Publishing Group
M3  - 10.1038/nn2015
N1  - 10.1038/nn2015
UR  - http://dx.doi.org/10.1038/nn2015
ER  -

TY  - JOUR
AU  - Tan, J.
TI  - Role of CD40 ligand in amyloidosis in transgenic Alzheimer's mice
JA  - Nat. Neurosci.
PY  - 2002///
VL  - 5
SP  - 1288
EP  - 1293
PB  - Nature Publishing Group
M3  - 10.1038/nn968
N1  - 10.1038/nn968
UR  - http://dx.doi.org/10.1038/nn968
ER  -
