The energy-regulating hormone leptin affects signals emerging from certain brain regions. New results explore the nature of these signals, finding a central role for phosphoinositide-3 kinase in the brain and the endocannabinoid system in adipocytes (pages 667–675).
This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
Mitochondrial Uncoupling Protein-2 (UCP2) Mediates Leptin Protection Against MPP+ Toxicity in Neuronal Cells
Neurotoxicity Research Open Access 10 September 2009
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Kim caesar
References
Buettner, C. et al. Nat. Med. 14, 667–675 (2008).
Ahima, R.S. et al. Nature 382, 250–252 (1996).
Myers, M.G., Cowley, M.A. & Munzberg, H. Annu. Rev. Physiol. 70, 537–556 (2008).
Bjorbaek, C. & Kahn, B.B. Recent Prog. Horm. Res. 59, 305–331 (2004).
Guo, K. et al. Endocrinology 148, 3987–3997 (2007).
Halaas, J.L. et al. Proc. Natl. Acad. Sci. USA 94, 8878–8883 (1997).
Cone, R.D. et al. Int. J. Obes. Relat. Metab. Disord. 25 Suppl 5, S63–S67 (2001).
Bates, S.H. et al. Nature 421, 856–859 (2003).
Gong, L. et al. Endocrinology published online, doi:10.1210/en.2007-0945 (10 April 2008).
Hill, J.W. et al. J. Clin. Invest. 118, 1796–1805 (2008).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Maratos-Flier, E. The long reach of leptin. Nat Med 14, 604–606 (2008). https://doi.org/10.1038/nm0608-604
Issue Date:
DOI: https://doi.org/10.1038/nm0608-604
This article is cited by
-
Mitochondrial Uncoupling Protein-2 (UCP2) Mediates Leptin Protection Against MPP+ Toxicity in Neuronal Cells
Neurotoxicity Research (2010)
