1. Dean Sheppard is in the Department of Medicine, University of California, San Francisco, UCSF Box 2922, San Francisco, California 94143-2922, USA.
   e-mail: dean.sheppard@ucsf.edu

Abstract

Allergens stimulate lymphocytes to become factories for secreted proteins that cause organ dysfunction in allergic diseases. Allergens are now shown to target dendritic cells, the cells responsible for processing and presenting antigens to T cells (pages 565–573).

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