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News and Views
Nature Medicine 14, 365 - 367 (2008)
doi:10.1038/nm0408-365
New drugs for an ancient parasite
Alex Loukas1 & Jeffrey M Bethony2
- Alex Loukas is in the Division of Infectious Diseases, Queensland Institute of Medical Research, 300 Herston Road, Brisbane, QLD 4006, Australia.
- Jeffrey M. Bethony is in the Department of Microbiology, Immunology and Tropical Medicine, George Washington University, 2300 Eye Street Northwest, Washington, DC 20037, USA. e-mail: Alex.Loukas@qimr.edu.au
Abstract
Only one drug is widely used to treat schistosomiasis, a chronic, neglected tropical disease caused by parasitic blood flukes. Fears of potential drug resistance have accelerated the search for new classes of antischistosome drugs. A promising candidate has now emerged (pages 407–412).
Schistosomiasis, caused by blood flukes of the genus Schistosoma (Fig. 1), has afflicted humans for thousands of years and is arguably the most important human helminth infection.
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