Figure 1 - Upregulation of MMP-9 in the DRG after SNL.

From the following article

Distinct roles of matrix metalloproteases in the early- and late-phase development of neuropathic pain

Yasuhiko Kawasaki, Zhen-Zhong Xu, Xiaoying Wang, Jong Yeon Park, Zhi-Ye Zhuang, Ping-Heng Tan, Yong-Jing Gao, Kristine Roy, Gabriel Corfas, Eng H Lo & Ru-Rong Ji

Nature Medicine 14, 331 - 336 (2008) Published online: 10 February 2008

doi:10.1038/nm1723

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(a) Gelatin zymography showing the time course of MMP-9 and MMP-2 activity in the injured L5 DRG of SNL rats. Bottom, intensity of specific MMP bands, expressed as multiples of the values in uninjured control (*P < 0.05 compared to control, n = 5). (b) MMP-9 western blot of the L5 DRGs of sham and SNL rats. Right, quantification of MMP-9 band intensity (*P < 0.05, n = 3). Tub, beta-tubulin. (c) MMP-9 immunohistochemistry in the L5 DRG of control and SNL rats. MMP-9 is expressed in DRG neurons. Scale bar, 50 mum. All data are mean plusminus s.e.m.

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