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From the following article

Differential regulation of central nervous system autoimmunity by TH1 and TH17 cells

Ingunn M Stromnes, Lauren M Cerretti, Denny Liggitt, Robert A Harris & Joan M Goverman

Nature Medicine 14, 337 - 342 (2008) Published online: 17 February 2008

doi:10.1038/nm1715

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Figure 1 - Unfortunately we are unable to provide accessible alternative text for this. If you require assistance to access this image, or to obtain a text description, please contact npg@nature.com

Figure 1

CNS autoimmunity differs in C3H MHC congenic mice.

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Figure 2

T cell skewing toward a TH17 or TH1 phenotype directs inflammation to the brain or spinal cord.

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Figure 3

IL-17 activity triggered by high TH17:TH1 ratios in the brain is required for parenchymal brain inflammation.

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Figure 4

TH17:TH1 ratio of epitope-specific T cells is influenced by functional avidity.

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