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Nature Medicine 14, 244 - 245 (2008)
doi:10.1038/nm0308-244
The weakness of a big heart
Thomas Force1
- Thomas Force is in the Center for Translational Medicine, Thomas Jefferson University, College Building, Rm. 316, 1025 Walnut St., Philadelphia, Pennsylvania 19107, USA. e-mail: thomas.force@jefferson.edu
Abstract
A well-known cell cycle regulator, p27KIP1, and protein kinase CK2-
´ mediate pathologic growth of cardiomyocytes. The findings have potential implications for the development of new treatment approaches to cardiac hypertrophy (pages 315–324).
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