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From the following article

Ex vivo glycan engineering of CD44 programs human multipotent mesenchymal stromal cell trafficking to bone

Robert Sackstein, Jasmeen S Merzaban, Derek W Cain, Nilesh M Dagia, Joel A Spencer, Charles P Lin & Roland Wohlgemuth

Nature Medicine 14, 181 - 187 (2008) Published online: 13 January 2008

doi:10.1038/nm1703

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Figure 1 - Unfortunately we are unable to provide accessible alternative text for this. If you require assistance to access this image, or to obtain a text description, please contact npg@nature.com

Figure 1

MSCs lack E-selectin ligands but express CD44 reactive with SACK-1 mAb, which recognizes a sialic acid–dependent epitope displayed on a CD44-specific N-glycan substitution.

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Figure 2

FTVI treatment of MSCs elaborates sialofucosylations on N-linked glycans of CD44, resulting in HCELL expression.

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Figure 3

HCELL+ MSCs have markedly enhanced shear-resistant adhesive interactions with endothelial E-selectin under defined shear stress conditions.

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Figure 4

Human MSC homing to mouse bone marrow.

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