Devil in the details - pp105 - 106

doi:10.1038/nm0208-105

Abstract - | Full Text - Devil in the details | PDF (103 KB) - Devil in the details

The doors of perception - p106

doi:10.1038/nm0208-106

Abstract - | Full Text - The doors of perception | PDF (47 KB) - The doors of perception

Europe pledges billions to solve its drug development woes - p107

Virginia Hughes

doi:10.1038/nm0208-107

Full Text - Europe pledges billions to solve its drug development woes | PDF (243 KB) - Europe pledges billions to solve its drug development woes

Battle over eye medicine gives drugmaker a dose of reality - p108

Erika Check Hayden

doi:10.1038/nm0208-108

Full Text - Battle over eye medicine gives drugmaker a dose of reality | PDF (157 KB) - Battle over eye medicine gives drugmaker a dose of reality

Patients flee, drawing attention to quarantine dilemma - p109

Alisa Opar

doi:10.1038/nm0208-109

Full Text - Patients flee, drawing attention to quarantine dilemma | PDF (218 KB) - Patients flee, drawing attention to quarantine dilemma

News in brief - pp110 - 111

doi:10.1038/nm0208-110

Abstract - | Full Text - News in brief | PDF (410 KB) - News in brief

Q & A: Frankie Trull - p112

Genevive Bjorn

doi:10.1038/nm0208-112

Abstract - | Full Text - Q & A: Frankie Trull | PDF (172 KB) - Q & A: Frankie Trull

A true vaccine pioneer - p113

Jeffrey Ulmer reviews Vaccinated: One Man's Quest to Defeat the World's Deadliest Diseases by Paul Offit

doi:10.1038/nm0208-113

Full Text - A true vaccine pioneer | PDF (108 KB) - A true vaccine pioneer

Saving face: rescuing a craniofacial birth defect - pp115 - 116

Sonja Jane McKeown & Marianne Bronner-Fraser

doi:10.1038/nm0208-115

Abstract - | Full Text - Saving face: rescuing a craniofacial birth defect | PDF (199 KB) - Saving face: rescuing a craniofacial birth defect

See also: Article by Jones et al.

Breathing easier with breast milk - pp116 - 118

Lynn Puddington & Adam Matson

doi:10.1038/nm0208-116

Abstract - | Full Text - Breathing easier with breast milk | PDF (238 KB) - Breathing easier with breast milk

See also: Letter by Verhasselt et al.

Safer, longer-lasting regulatory T cells with -catenin - pp118 - 119

Jeffrey A Bluestone & Matthias Hebrok

doi:10.1038/nm0208-118

Abstract - | Full Text - Safer, longer-lasting regulatory T cells with -catenin | PDF (533 KB) - Safer, longer-lasting regulatory T cells with -catenin

See also: Article by Ding et al.

A deader vaccine? - pp120 - 121

Philip Minor

doi:10.1038/nm0208-120

Abstract - | Full Text - A deader vaccine? | PDF (229 KB) - A deader vaccine?

See also: Article by Vignuzzi et al.

Research Highlights - pp122 - 123

doi:10.1038/nm0208-122

Full Text - Research Highlights | PDF (272 KB) - Research Highlights

Prevention of the neurocristopathy Treacher Collins syndrome through inhibition of p53 function - pp125 - 133

Natalie C Jones, Megan L Lynn, Karin Gaudenz, Daisuke Sakai, Kazushi Aoto, Jean-Phillipe Rey, Earl F Glynn, Lacey Ellington, Chunying Du, Jill Dixon, Michael J Dixon & Paul A Trainor

doi:10.1038/nm1725

Abstract - | Full Text - Prevention of the neurocristopathy Treacher Collins syndrome through inhibition of p53 function | PDF (579 KB) - Prevention of the neurocristopathy Treacher Collins syndrome through inhibition of p53 function | Supplementary information

See also: News and Views by McKeown & Bronner-Fraser

Functional skeletal muscle regeneration from differentiating embryonic stem cells - pp134 - 143

Radbod Darabi, Kimberly Gehlbach, Robert M Bachoo, Shwetha Kamath, Mitsujiro Osawa, Kristine E Kamm, Michael Kyba & Rita C R Perlingeiro

doi:10.1038/nm1705

Abstract - | Full Text - Functional skeletal muscle regeneration from differentiating embryonic stem cells | PDF (1,088 KB) - Functional skeletal muscle regeneration from differentiating embryonic stem cells | Supplementary information

Dual role of proapoptotic BAD in insulin secretion and beta cell survival - pp144 - 153

Nika N Danial, Loren D Walensky, Chen-Yu Zhang, Cheol Soo Choi, Jill K Fisher, Anthony J A Molina, Sandeep Robert Datta, Kenneth L Pitter, Gregory H Bird, Jakob D Wikstrom, Jude T Deeney, Kirsten Robertson, Joel Morash, Ameya Kulkarni, Susanne Neschen, Sheene Kim, Michael E Greenberg, Barbara E Corkey, Orian S Shirihai, Gerald I Shulman, Bradford B Lowell & Stanley J Korsmeyer

doi:10.1038/nm1717

Abstract - | Full Text - Dual role of proapoptotic BAD in insulin secretion and beta cell survival | PDF (714 KB) - Dual role of proapoptotic BAD in insulin secretion and beta cell survival | Supplementary information

Engineering attenuated virus vaccines by controlling replication fidelity - pp154 - 161

Marco Vignuzzi, Emily Wendt & Raul Andino

doi:10.1038/nm1726

Abstract - | Full Text - Engineering attenuated virus vaccines by controlling replication fidelity | PDF (280 KB) - Engineering attenuated virus vaccines by controlling replication fidelity | Supplementary information

See also: News and Views by Minor

Beta-catenin stabilization extends regulatory T cell survival and induces anergy in nonregulatory T cells - pp162 - 169

Yi Ding, Shiqian Shen, Andreia C Lino, Maria A Curotto de Lafaille & Juan J Lafaille

doi:10.1038/nm1707

Abstract - | Full Text - Beta-catenin stabilization extends regulatory T cell survival and induces anergy in nonregulatory T cells | PDF (547 KB) - Beta-catenin stabilization extends regulatory T cell survival and induces anergy in nonregulatory T cells | Supplementary information

See also: News and Views by Bluestone & Hebrok

Breast milk–mediated transfer of an antigen induces tolerance and protection from allergic asthma - pp170 - 175

Valérie Verhasselt, Valérie Milcent, Julie Cazareth, Akira Kanda, Sébastien Fleury, David Dombrowicz, Nicolas Glaichenhaus & Valérie Julia

doi:10.1038/nm1718

First paragraph - | Full Text - Breast milk–mediated transfer of an antigen induces tolerance and protection from allergic asthma | PDF (344 KB) - Breast milk–mediated transfer of an antigen induces tolerance and protection from allergic asthma | Supplementary information

See also: News and Views by Puddington & Matson

Dcir deficiency causes development of autoimmune diseases in mice due to excess expansion of dendritic cells - pp176 - 180

Noriyuki Fujikado, Shinobu Saijo, Tomo Yonezawa, Kazusuke Shimamori, Akina Ishii, Sho Sugai, Hayato Kotaki, Katsuko Sudo, Masato Nose & Yoichiro Iwakura

doi:10.1038/nm1697

First paragraph - | Full Text - Dcir deficiency causes development of autoimmune diseases in mice due to excess expansion of dendritic cells | PDF (411 KB) - Dcir deficiency causes development of autoimmune diseases in mice due to excess expansion of dendritic cells | Supplementary information

Ex vivo glycan engineering of CD44 programs human multipotent mesenchymal stromal cell trafficking to bone - pp181 - 187

Robert Sackstein, Jasmeen S Merzaban, Derek W Cain, Nilesh M Dagia, Joel A Spencer, Charles P Lin & Roland Wohlgemuth

doi:10.1038/nm1703

First paragraph - | Full Text - Ex vivo glycan engineering of CD44 programs human multipotent mesenchymal stromal cell trafficking to bone | PDF (439 KB) - Ex vivo glycan engineering of CD44 programs human multipotent mesenchymal stromal cell trafficking to bone | Supplementary information

Dok1 mediates high-fat diet–induced adipocyte hypertrophy and obesity through modulation of PPAR- phosphorylation - pp188 - 193

Tetsuya Hosooka, Tetsuya Noguchi, Ko Kotani, Takehiro Nakamura, Hiroshi Sakaue, Hiroshi Inoue, Wataru Ogawa, Kazutoshi Tobimatsu, Kazuo Takazawa, Mashito Sakai, Yasushi Matsuki, Ryuji Hiramatsu, Tomoharu Yasuda, Mitchell A Lazar, Yuji Yamanashi & Masato Kasuga

doi:10.1038/nm1706

First paragraph - | Full Text - Dok1 mediates high-fat diet–induced adipocyte hypertrophy and obesity through modulation of PPAR- phosphorylation | PDF (309 KB) - Dok1 mediates high-fat diet–induced adipocyte hypertrophy and obesity through modulation of PPAR- phosphorylation | Supplementary information

Oxidative damage–induced inflammation initiates age-related macular degeneration - pp194 - 198

Joe G Hollyfield, Vera L Bonilha, Mary E Rayborn, Xiaoping Yang, Karen G Shadrach, Liang Lu, Rafael L Ufret, Robert G Salomon & Victor L Perez

doi:10.1038/nm1709

First paragraph - | Full Text - Oxidative damage–induced inflammation initiates age-related macular degeneration | PDF (502 KB) - Oxidative damage–induced inflammation initiates age-related macular degeneration | Supplementary information

Mouse models of rhinovirus-induced disease and exacerbation of allergic airway inflammation - pp199 - 204

Nathan W Bartlett, Ross P Walton, Michael R Edwards, Juliya Aniscenko, Gaetano Caramori, Jie Zhu, Nicholas Glanville, Katherine J Choy, Patrick Jourdan, Jerome Burnet, Tobias J Tuthill, Michael S Pedrick, Michael J Hurle, Chris Plumpton, Nigel A Sharp, James N Bussell, Dallas M Swallow, Jurgen Schwarze, Bruno Guy, Jeffrey W Almond, Peter K Jeffery, Clare M Lloyd, Alberto Papi, Richard A Killington, David J Rowlands, Edward D Blair, Neil J Clarke & Sebastian L Johnston

doi:10.1038/nm1713

Abstract - | Full Text - Mouse models of rhinovirus-induced disease and exacerbation of allergic airway inflammation | PDF (522 KB) - Mouse models of rhinovirus-induced disease and exacerbation of allergic airway inflammation | Supplementary information

Targeting of antigen to the herpesvirus entry mediator augments primary adaptive immune responses - pp205 - 212

Marcio O Lasaro, Nia Tatsis, Scott E Hensley, J Charles Whitbeck, Shih-Wen Lin, John J Rux, E John Wherry, Gary H Cohen, Roselyn J Eisenberg & Hildegund C Ertl

doi:10.1038/nm1704

First paragraph - | Full Text - Targeting of antigen to the herpesvirus entry mediator augments primary adaptive immune responses | PDF (423 KB) - Targeting of antigen to the herpesvirus entry mediator augments primary adaptive immune responses | Supplementary information

Perfusion-decellularized matrix: using nature's platform to engineer a bioartificial heart - pp213 - 221

Harald C Ott, Thomas S Matthiesen, Saik-Kia Goh, Lauren D Black, Stefan M Kren, Theoden I Netoff & Doris A Taylor

doi:10.1038/nm1684

First paragraph - | Full Text - Perfusion-decellularized matrix: using nature's platform to engineer a bioartificial heart | PDF (1,317 KB) - Perfusion-decellularized matrix: using nature's platform to engineer a bioartificial heart | Supplementary information

Corrigendum: G₁₂-G₁₃–LARG–mediated signaling in vascular smooth muscle is required for salt-induced hypertension - p222

Angela Wirth, Zoltán Benyó, Martina Lukasova, Barbara Leutgeb, Nina Wettschureck, Stefan Gorbey, Petra Örsy, Béla Horváth, Christiane Maser-Gluth, Erich Greiner, Björn Lemmer, Günther Schütz, Silvio Gutkind & Stefan Offermanns

doi:10.1038/nm0208-222

Full Text - Corrigendum: G12-G13–LARG–mediated signaling in vascular smooth muscle is required for salt-induced hypertension | PDF (43 KB) - Corrigendum: G12-G13–LARG–mediated signaling in vascular smooth muscle is required for salt-induced hypertension