News and Views
Nature Medicine 14, 1152 - 1153 (2008)
doi:10.1038/nm1108-1152
RIG-ing an antitumor response
Fabio Petrocca1 & Judy Lieberman1
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Fabio Petrocca and Judy Lieberman are at the Immune Disease Institute and Department of Pediatrics, Harvard Medical School, 200 Longwood Avenue, Boston, Massachusetts, 02115, USA.
e-mail: lieberman@idi.harvard.edu
Abstract
A small interfering RNA has been engineered to silence an oncogene and activate the immune response simultaneously. The approach shrinks tumors in mice (pages 1256–1263).
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