1. Fabio Petrocca and Judy Lieberman are at the Immune Disease Institute and Department of Pediatrics, Harvard Medical School, 200 Longwood Avenue, Boston, Massachusetts, 02115, USA.
   e-mail: lieberman@idi.harvard.edu

Abstract

A small interfering RNA has been engineered to silence an oncogene and activate the immune response simultaneously. The approach shrinks tumors in mice (pages 1256–1263).

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