TY - JOUR AU - Ross, R. TI - Atherosclerosis[mdash]an inflammatory disease JA - N. Engl. J. Med. PY - 1999/// VL - 340 SP - 115 EP - 126 PB - Nature Publishing Group M3 - 10.1056/NEJM199901143400207 N1 - 10.1056/NEJM199901143400207 UR - http://dx.doi.org/10.1056/NEJM199901143400207 ER - TY - JOUR AU - Hansson, G.K. AU - Libby, P. TI - The immune response in atherosclerosis: a double-edged sword JA - Nat. Rev. Immunol. PY - 2006/// VL - 6 SP - 508 EP - 519 PB - Nature Publishing Group M3 - 10.1038/nri1882 N1 - 10.1038/nri1882 UR - http://dx.doi.org/10.1038/nri1882 ER - TY - JOUR AU - Steinberg, D. TI - Thematic review series: the pathogenesis of atherosclerosis. An interpretive history of the cholesterol controversy, part V: the discovery of the statins and the end of the controversy JA - J. Lipid Res. PY - 2006/// VL - 47 SP - 1339 EP - 1351 PB - Nature Publishing Group M3 - 10.1194/jlr.R600009-JLR200 N1 - 10.1194/jlr.R600009-JLR200 UR - http://dx.doi.org/10.1194/jlr.R600009-JLR200 ER - TY - JOUR AU - Witztum, J.L. TI - The oxidation hypothesis of atherosclerosis JA - Lancet PY - 1994/// VL - 344 SP - 793 EP - 795 PB - Nature Publishing Group M3 - 10.1016/S0140-6736(94)92346-9 N1 - 10.1016/S0140-6736(94)92346-9 UR - http://dx.doi.org/10.1016/S0140-6736(94)92346-9 ER - TY - JOUR AU - Shah, P.K. TI - Molecular mechanisms of plaque instability JA - Curr. Opin. Lipidol. PY - 2007/// VL - 18 SP - 492 EP - 499 PB - Nature Publishing Group ER - TY - JOUR AU - Kolodgie, F.D. TI - Intraplaque hemorrhage and progression of coronary atheroma JA - N. Engl. J. Med. PY - 2003/// VL - 349 SP - 2316 EP - 2325 PB - Nature Publishing Group M3 - 10.1056/NEJMoa035655 N1 - 10.1056/NEJMoa035655 UR - http://dx.doi.org/10.1056/NEJMoa035655 ER - TY - JOUR AU - Virmani, R. TI - Lessons from sudden coronary death: a comprehensive morphological classification scheme for atherosclerotic lesions JA - Arterioscler. Thromb. Vasc. Biol. PY - 2000/// VL - 20 SP - 1262 EP - 1275 PB - Nature Publishing Group ER - TY - JOUR AU - Spagnoli, L.G. TI - Extracranial thrombotically active carotid plaque as a risk factor for ischemic stroke JA - J. Am. Med. Assoc. PY - 2004/// VL - 292 SP - 1845 EP - 1852 PB - Nature Publishing Group M3 - 10.1001/jama.292.15.1845 N1 - 10.1001/jama.292.15.1845 UR - http://dx.doi.org/10.1001/jama.292.15.1845 ER - TY - JOUR AU - McIntyre, T.M. TI - Biologically active oxidized phospholipids JA - J. Biol. Chem. PY - 1999/// VL - 274 SP - 25189 EP - 25192 PB - Nature Publishing Group M3 - 10.1074/jbc.274.36.25189 N1 - 10.1074/jbc.274.36.25189 UR - http://dx.doi.org/10.1074/jbc.274.36.25189 ER - TY - JOUR AU - Prescott, S.M. TI - Platelet-activating factor and related lipid mediators JA - Annu. Rev. Biochem. PY - 2000/// VL - 69 SP - 419 EP - 445 PB - Nature Publishing Group M3 - 10.1146/annurev.biochem.69.1.419 N1 - 10.1146/annurev.biochem.69.1.419 UR - http://dx.doi.org/10.1146/annurev.biochem.69.1.419 ER - TY - JOUR AU - Macphee, C.H. AU - Nelson, J.J. AU - Zalewski, A. TI - Lipoprotein-associated phospholipase A2 as a target of therapy JA - Curr. Opin. Lipidol. PY - 2005/// VL - 16 SP - 442 EP - 446 PB - Nature Publishing Group M3 - 10.1097/01.mol.0000174155.61307.5f N1 - 10.1097/01.mol.0000174155.61307.5f UR - http://dx.doi.org/10.1097/01.mol.0000174155.61307.5f ER - TY - JOUR AU - Zalewski, A. AU - Macphee, C. TI - Role of lipoprotein-associated phospholipase A2 in atherosclerosis: biology, epidemiology, and possible therapeutic target JA - Arterioscler. Thromb. Vasc. Biol. PY - 2005/// VL - 25 SP - 923 EP - 931 PB - Nature Publishing Group M3 - 10.1161/01.ATV.0000160551.21962.a7 N1 - 10.1161/01.ATV.0000160551.21962.a7 UR - http://dx.doi.org/10.1161/01.ATV.0000160551.21962.a7 ER - TY - JOUR AU - Tsimikas, S. AU - Tsironis, L.D. AU - Tselepis, A.D. TI - New insights into the role of lipoprotein(a)-associated lipoprotein-associated phospholipase A2 in atherosclerosis and cardiovascular disease JA - Arterioscler. Thromb. Vasc. Biol. PY - 2007/// VL - 27 SP - 2094 EP - 2099 PB - Nature Publishing Group M3 - 10.1161/01.atv.0000280571.28102.d4 N1 - 10.1161/01.atv.0000280571.28102.d4 UR - http://dx.doi.org/10.1161/01.atv.0000280571.28102.d4 ER - TY - JOUR AU - Garza, C.A. TI - Association between lipoprotein-associated phospholipase A2 and cardiovascular disease: a systematic review JA - Mayo Clin. Proc. PY - 2007/// VL - 82 SP - 159 EP - 165 PB - Nature Publishing Group ER - TY - JOUR AU - Macphee, C.H. TI - Lipoprotein-associated phospholipase A2, platelet-activating factor acetylhydrolase, generates two bioactive products during the oxidation of low-density lipoprotein: use of a novel inhibitor JA - Biochem. J. PY - 1999/// VL - 338 SP - 479 EP - 487 PB - Nature Publishing Group M3 - 10.1042/0264-6021:3380479 N1 - 10.1042/0264-6021:3380479 UR - http://dx.doi.org/10.1042/0264-6021:3380479 ER - TY - JOUR AU - Davis, B. TI - Electrospray ionization mass spectrometry identifies substrates and products of lipoprotein-associated phospholipase A2 in oxidized human low density lipoprotein JA - J. Biol. Chem. PY - 2008/// VL - 283 SP - 6428 EP - 6437 PB - Nature Publishing Group M3 - 10.1074/jbc.M709970200 N1 - 10.1074/jbc.M709970200 UR - http://dx.doi.org/10.1074/jbc.M709970200 ER - TY - JOUR AU - Kougias, P. TI - Lysophosphatidylcholine and secretory phospholipase A2 in vascular disease: mediators of endothelial dysfunction and atherosclerosis JA - Med. Sci. Monit. PY - 2006/// VL - 12 SP - RA5 EP - RA16 PB - Nature Publishing Group ER - TY - JOUR AU - Shi, Y. TI - Role of lipoprotein-associated phospholipase A2 in leukocyte activation and inflammatory responses JA - Atherosclerosis PY - 2007/// VL - 191 SP - 54 EP - 62 PB - Nature Publishing Group M3 - 10.1016/j.atherosclerosis.2006.05.001 N1 - 10.1016/j.atherosclerosis.2006.05.001 UR - http://dx.doi.org/10.1016/j.atherosclerosis.2006.05.001 ER - TY - JOUR AU - Carpenter, K.L. TI - Mildly oxidised LDL induces more macrophage death than moderately oxidised LDL: roles of peroxidation, lipoprotein-associated phospholipase A2 and PPAR[gamma] JA - FEBS Lett. PY - 2003/// VL - 553 SP - 145 EP - 150 PB - Nature Publishing Group M3 - 10.1016/S0014-5793(03)01007-X N1 - 10.1016/S0014-5793(03)01007-X UR - http://dx.doi.org/10.1016/S0014-5793(03)01007-X ER - TY - JOUR AU - Perez, R. TI - Involvement of group VIA calcium-independent phospholipase A2 in macrophage engulfment of hydrogen peroxide-treated U937 cells JA - J. Immunol. PY - 2006/// VL - 176 SP - 2555 EP - 2561 PB - Nature Publishing Group ER - TY - JOUR AU - Aprahamian, T. TI - Impaired clearance of apoptotic cells promotes synergy between atherogenesis and autoimmune disease JA - J. Exp. Med. PY - 2004/// VL - 199 SP - 1121 EP - 1131 PB - Nature Publishing Group M3 - 10.1084/jem.20031557 N1 - 10.1084/jem.20031557 UR - http://dx.doi.org/10.1084/jem.20031557 ER - TY - JOUR AU - Kolodgie, F.D. TI - Lipoprotein-associated phospholipase A2 protein expression in the natural progression of human coronary atherosclerosis JA - Arterioscler. Thromb. Vasc. Biol. PY - 2006/// VL - 26 SP - 2523 EP - 2529 PB - Nature Publishing Group M3 - 10.1161/01.ATV.0000244681.72738.bc N1 - 10.1161/01.ATV.0000244681.72738.bc UR - http://dx.doi.org/10.1161/01.ATV.0000244681.72738.bc ER - TY - JOUR AU - Blackie, J.A. TI - The identification of clinical candidate SB-480848: a potent inhibitor of lipoprotein-associated phospholipase A2 JA - Bioorg. Med. Chem. Lett. PY - 2003/// VL - 13 SP - 1067 EP - 1070 PB - Nature Publishing Group M3 - 10.1016/S0960-894X(03)00058-1 N1 - 10.1016/S0960-894X(03)00058-1 UR - http://dx.doi.org/10.1016/S0960-894X(03)00058-1 ER - TY - JOUR AU - Gerrity, R.G. TI - Diabetes-induced accelerated atherosclerosis in swine JA - Diabetes PY - 2001/// VL - 50 SP - 1654 EP - 1665 PB - Nature Publishing Group M3 - 10.2337/diabetes.50.7.1654 N1 - 10.2337/diabetes.50.7.1654 UR - http://dx.doi.org/10.2337/diabetes.50.7.1654 ER - TY - JOUR AU - Mohler, E.R., TI - Site-specific atherogenic gene expression correlates with subsequent variable lesion development in coronary and peripheral vasculature JA - Arterioscler. Thromb. Vasc. Biol. PY - 2008/// VL - 28 SP - 850 EP - 855 PB - Nature Publishing Group M3 - 10.1161/ATVBAHA.107.154534 N1 - 10.1161/ATVBAHA.107.154534 UR - http://dx.doi.org/10.1161/ATVBAHA.107.154534 ER - TY - JOUR AU - Chatzizisis, Y.S. TI - Role of endothelial shear stress in the natural history of coronary atherosclerosis and vascular remodeling: molecular, cellular and vascular behavior JA - J. Am. Coll. Cardiol. PY - 2007/// VL - 49 SP - 2379 EP - 2393 PB - Nature Publishing Group M3 - 10.1016/j.jacc.2007.02.059 N1 - 10.1016/j.jacc.2007.02.059 UR - http://dx.doi.org/10.1016/j.jacc.2007.02.059 ER - TY - JOUR AU - Jo, H. TI - Role of NADPH oxidases in disturbed flow- and BMP4- induced inflammation and atherosclerosis JA - Antioxid. Redox Signal. PY - 2006/// VL - 8 SP - 1609 EP - 1619 PB - Nature Publishing Group M3 - 10.1089/ars.2006.8.1609 N1 - 10.1089/ars.2006.8.1609 UR - http://dx.doi.org/10.1089/ars.2006.8.1609 ER - TY - JOUR AU - Schaloske, R.H. AU - Dennis, E.A. TI - The phospholipase A2 superfamily and its group numbering system JA - Biochim. Biophys. Acta PY - 2006/// VL - 1761 SP - 1246 EP - 1259 PB - Nature Publishing Group ER - TY - JOUR AU - Gardner, A.A. AU - Reichert, E.C. AU - Topham, M.K. AU - Stafforini, D.M. TI - Identification of a domain that mediates association of platelet-activating factor acetylhydrolase with high-density lipoprotein JA - J. Biol. Chem. PY - 2008/// VL - 283 SP - 17099 EP - 17106 PB - Nature Publishing Group M3 - 10.1074/jbc.M802394200 N1 - 10.1074/jbc.M802394200 UR - http://dx.doi.org/10.1074/jbc.M802394200 ER - TY - JOUR AU - Stafforini, D.M. TI - Molecular basis of the interaction between plasma platelet-activating factor acetylhydrolase and low density lipoprotein JA - J. Biol. Chem. PY - 1999/// VL - 274 SP - 7018 EP - 7024 PB - Nature Publishing Group M3 - 10.1074/jbc.274.11.7018 N1 - 10.1074/jbc.274.11.7018 UR - http://dx.doi.org/10.1074/jbc.274.11.7018 ER - TY - JOUR AU - Heller, E.A. TI - Chemokine CXCL10 promotes atherogenesis by modulating the local balance of effector and regulatory T cells JA - Circulation PY - 2006/// VL - 113 SP - 2301 EP - 2312 PB - Nature Publishing Group M3 - 10.1161/CIRCULATIONAHA.105.605121 N1 - 10.1161/CIRCULATIONAHA.105.605121 UR - http://dx.doi.org/10.1161/CIRCULATIONAHA.105.605121 ER - TY - JOUR AU - Swirski, F.K. TI - Ly-6Chi monocytes dominate hypercholesterolemia-associated monocytosis and give rise to macrophages in atheromata JA - J. Clin. Invest. PY - 2007/// VL - 117 SP - 195 EP - 205 PB - Nature Publishing Group M3 - 10.1172/JCI29950 N1 - 10.1172/JCI29950 UR - http://dx.doi.org/10.1172/JCI29950 ER - TY - JOUR AU - Papaspyridonos, M. TI - Novel candidate genes in unstable areas of human atherosclerotic plaques JA - Arterioscler. Thromb. Vasc. Biol. PY - 2006/// VL - 26 SP - 1837 EP - 1844 PB - Nature Publishing Group M3 - 10.1161/01.ATV.0000229695.68416.76 N1 - 10.1161/01.ATV.0000229695.68416.76 UR - http://dx.doi.org/10.1161/01.ATV.0000229695.68416.76 ER - TY - JOUR AU - Reddy, V.y. AU - Zhang, Z.-Y. AU - Weiss, S.J. TI - Pericellular mobilization of the tissue-destructive cysteine proteinases, cathepsins B, L and S by human monocyte-derived macrophages JA - Proc. Natl. Acad. Sci. USA PY - 1995/// VL - 92 SP - 3849 EP - 3853 PB - Nature Publishing Group M3 - 10.1073/pnas.92.9.3849 N1 - 10.1073/pnas.92.9.3849 UR - http://dx.doi.org/10.1073/pnas.92.9.3849 ER - TY - JOUR TI - MRC/BHF Heart Protection Study of cholesterol-lowering with simvastatin in 5693 people with diabetes: a randomized placebo-controlled trial JA - Lancet PY - 2003/// VL - 361 SP - 2005 EP - 2013 PB - Nature Publishing Group M3 - 10.1016/S0140-6736(03)13636-7 N1 - 10.1016/S0140-6736(03)13636-7 UR - http://dx.doi.org/10.1016/S0140-6736(03)13636-7 ER - TY - JOUR AU - Moreno, P.R. TI - Coronary composition and macrophage infiltration in atherectomy specimens from patients with diabetes mellitus JA - Circulation PY - 2000/// VL - 102 SP - 2180 EP - 2184 PB - Nature Publishing Group ER - TY - JOUR AU - Burke, A.P. TI - Morphologic findings of coronary atherosclerotic plaques in diabetics: a postmortem study JA - Arterioscler. Thromb. Vasc. Biol. PY - 2004/// VL - 24 SP - 1266 EP - 1271 PB - Nature Publishing Group M3 - 10.1161/01.ATV.0000131783.74034.97 N1 - 10.1161/01.ATV.0000131783.74034.97 UR - http://dx.doi.org/10.1161/01.ATV.0000131783.74034.97 ER - TY - JOUR AU - Pennathur, S. AU - Heinecke, J.W. TI - Mechanisms for oxidative stress in diabetic cardiovascular disease JA - Antioxid. Redox Signal. PY - 2007/// VL - 9 SP - 955 EP - 969 PB - Nature Publishing Group M3 - 10.1089/ars.2007.1595 N1 - 10.1089/ars.2007.1595 UR - http://dx.doi.org/10.1089/ars.2007.1595 ER - TY - JOUR AU - Tacke, F. TI - Monocyte subsets differentially employ CCR2, CCR5 and CX3CR1 to accumulate within atherosclerotic plaques JA - J. Clin. Invest. PY - 2007/// VL - 117 SP - 185 EP - 194 PB - Nature Publishing Group M3 - 10.1172/JCI28549 N1 - 10.1172/JCI28549 UR - http://dx.doi.org/10.1172/JCI28549 ER - TY - JOUR AU - Navab, M. TI - The oxidation hypothesis of atherogenesis: the role of oxidized phospholipids and HDL JA - J. Lipid Res. PY - 2004/// VL - 45 SP - 993 EP - 1007 PB - Nature Publishing Group M3 - 10.1194/jlr.R400001-JLR200 N1 - 10.1194/jlr.R400001-JLR200 UR - http://dx.doi.org/10.1194/jlr.R400001-JLR200 ER - TY - JOUR AU - Sangvanich, P. AU - Mackness, B. AU - Gaskell, S.J. AU - Durrington, P. AU - Mackness, M. TI - The effect of high-density lipoproteins on the formation of lipid/protein conjugates during in vitro oxidation of low-density lipoprotein JA - Biochem. Biophys. Res. Commun. PY - 2003/// VL - 300 SP - 501 EP - 506 PB - Nature Publishing Group M3 - 10.1016/S0006-291X(02)02849-8 N1 - 10.1016/S0006-291X(02)02849-8 UR - http://dx.doi.org/10.1016/S0006-291X(02)02849-8 ER - TY - JOUR AU - Getz, G.S. AU - Reardon, C.A. TI - Diet and murine atherosclerosis JA - Arterioscler. Thromb. Vasc. Biol. PY - 2006/// VL - 26 SP - 242 EP - 249 PB - Nature Publishing Group M3 - 10.1161/01.ATV.0000201071.49029.17 N1 - 10.1161/01.ATV.0000201071.49029.17 UR - http://dx.doi.org/10.1161/01.ATV.0000201071.49029.17 ER - TY - JOUR AU - Caslake, M.J. TI - Lipoprotein-associated phospholipase A2, platelet-activating factor acetylhydrolase: a potential new risk factor for coronary artery disease JA - Atherosclerosis PY - 2000/// VL - 150 SP - 413 EP - 419 PB - Nature Publishing Group M3 - 10.1016/S0021-9150(99)00406-2 N1 - 10.1016/S0021-9150(99)00406-2 UR - http://dx.doi.org/10.1016/S0021-9150(99)00406-2 ER - TY - JOUR AU - Van Eck, M. TI - Bone marrow transplantation in apolipoprotein E-deficient mice. Effect of ApoE gene dosage on serum lipid concentrations, [beta]VLDL catabolism, and atherosclerosis JA - Arterioscler. Thromb. Vasc. Biol. PY - 1997/// VL - 17 SP - 3117 EP - 3126 PB - Nature Publishing Group ER - TY - JOUR AU - Singer, A.G. TI - Interfacial kinetic and binding properties of the complete set of human and mouse groups I, II, V, X and XII secreted phospholipases A2 JA - J. Biol. Chem. PY - 2002/// VL - 277 SP - 48535 EP - 48549 PB - Nature Publishing Group M3 - 10.1074/jbc.M205855200 N1 - 10.1074/jbc.M205855200 UR - http://dx.doi.org/10.1074/jbc.M205855200 ER - TY - JOUR AU - Smart, B.P. TI - Inhibition of the complete set of mammalian secreted phospholipases A2 by indole analogues: a structure-guided study JA - Bioorg. Med. Chem. PY - 2004/// VL - 12 SP - 1737 EP - 1749 PB - Nature Publishing Group M3 - 10.1016/j.bmc.2004.01.022 N1 - 10.1016/j.bmc.2004.01.022 UR - http://dx.doi.org/10.1016/j.bmc.2004.01.022 ER -