News and Views


Nature Medicine 14, 1018 - 1019 (2008)
doi:10.1038/nm1008-1018

Autoantibodies vex the vasculature

Cees GM Kallenberg1, Coen A Stegeman2 & Peter Heeringa3

  1. Cees G.M. Kallenberg is in the Department of Rheumatology and Clinical Immunology, University of Groningen, Hanzeplein, P.O. Box 30.001, Groningen 9700RB, The Netherlands.
    e-mail: c.g.m.kallenberg@int.umcg.nl
  2. Coen A. Stegeman is in the Department of Nephrology, University of Groningen, Hanzeplein, P.O. Box 30.001, Groningen 9700RB, The Netherlands.
  3. Peter Heeringa is in the Department of Medical Biology, University Medical Center Groningen, University of Groningen, Hanzeplein, P.O. Box 30.001, Groningen 9700RB, The Netherlands.


Infections with fimbriated bacteria may trigger autoimmunity and cause a form of severe vasculitis that affects capillaries in the kidney and that can destroy the organ (pages 1088–1096).

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