News and Views


Nature Medicine 14, 1016 - 1018 (2008)
doi:10.1038/nm1008-1016

Immune alteration fends off AIDS

Karen O'Connell1 & Robert F Siliciano1

  1. Karen O'Connell and Robert F. Siliciano are in the Department of Medicine, and Robert F. Siliciano is in the Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, 733 North Broadway, Baltimore, Maryland 21205, USA.
    e-mail: rsiliciano@jhmi.edu


Comparative studies of the immune response to simian immunodeficiency virus in two nonhuman primate species provide insight into a central aspect of HIV infection—the ability of the virus to cause chronic activation of the immune system (pages 1077–1087).

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