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Letter

Nature Medicine 14, 75–80 (1 January 2008) | doi:10.1038/nm1693

Adenosine is crucial for deep brain stimulation|[ndash]|mediated attenuation of tremor

Lane Bekar , Witold Libionka , Guo-Feng Tian , Qiwu Xu , Arnulfo Torres , Xiaohai Wang , Ditte Lovatt , Erika Williams , Takahiro Takano , Jurgen Schnermann , Robert Bakos & Maiken Nedergaard

Deep brain stimulation (DBS) is a widely used neurosurgical approach to treating tremor and other movement disorders. In addition, the use of DBS in a number of psychiatric diseases, including obsessive-compulsive disorders and depression, is currently being tested.