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News and Views
Nature Medicine 14, 19 - 20 (2008)
doi:10.1038/nm0108-19
Short-circuit recovery from spinal injury
Dennis J Stelzner1
- Dennis J. Stelzner is in the Department of Cell and Developmental Biology, State University of New York Upstate Medical University, Syracuse, New York 13210, USA. e-mail: stelzned@upstate.edu
Abstract
Propriospinal neurons, whose axons never leave the spinal cord, aid in recovery after spinal cord injury—even when all axons from the brain have been damaged (pages 69–74).
There are no proven therapies that enhance axonal regeneration and restore function after complete spinal cord injury in people. However, progress has been made in identifying factors in the spinal cord environment that inhibit regrowth of damaged axons and in developing strategies to neutralize these factors or increase the growth response of neurons to overcome them.
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