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Recovery of supraspinal control of stepping via indirect propriospinal relay connections after spinal cord injury

Gregoire Courtine, Bingbing Song, Roland R Roy, Hui Zhong, Julia E Herrmann, Yan Ao, Jingwei Qi, V Reggie Edgerton & Michael V Sofroniew

Nature Medicine 14, 69 - 74 (2008) Published online: 6 January 2008

doi:10.1038/nm1682

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Figure 1 - Unfortunately we are unable to provide accessible alternative text for this. If you require assistance to access this image, or to obtain a text description, please contact npg@nature.com

Figure 1

Recovery of supraspinal control of stepping after a lateral hemisection at T12.

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Figure 2

Long-term loss of supraspinal but not propriospinal connections after a T12 lateral hemisection or after T12 (left) and delayed T7 (right) lateral hemisections.

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Figure 3

Recovery of supraspinal control of stepping after delayed but not simultaneous T12 (left) and T7 (right) lateral hemisections.

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Figure 4

Excitotoxic ablation of T8–T10 neurons abolishes the recovered control of stepping after a T12 lateral hemisection and after a T12 lateral hemisection followed by a delayed T7 lateral hemisection.

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