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Nature Medicine 14, 20 - 21 (2008)
doi:10.1038/nm0108-20
From lung injury to fibrosis
Klaus Ley1 & Alexander Zarbock2
- Klaus Ley is in the La Jolla Institute for Allergy and Immunology, La Jolla, California 92037, USA. e-mail: klaus@liai.org
- Alexander Zarbock is in the Department of Anesthesiology and Intensive Care Medicine, University of Münster, Münster 48129, Germany.
Abstract
Two hallmarks of lung fibrosis are vascular leakage and recruitment of fibroblasts into the alveoli. Lysophosphatidic acid is now implicated as a major regulator of both parameters (pages 45–54).
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