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Nature Medicine 13, 1020–1021 (1 September 2007) | doi:10.1038/nm0907-1020

Diseased red blood cells topple iron balance

Stella T Chou & Mitchell J Weiss

Healthy bodies are fastidious about iron. This essential nutrient is required for the function of many endogenous proteins, most predominantly the red blood cell (RBC) oxygen transporter hemoglobin.