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News and Views
Nature Medicine 13, 1018 - 1019 (2007)
doi:10.1038/nm0907-1018
Schizophrenia drug says goodbye to dopamine
Daniel R Weinberger1
- Daniel R. Weinberger is at the Clinical Brain Disorders Branch, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, USA. e-mail: daniel.weinberger@mail.nih.gov
Abstract
A drug that activates glutamate receptors offers promise for a new class of anti-psychotic therapeutics and sheds light on the pathophysiology of this devastating disease (pages 1102–1107).
All psychiatric drugs in common use today are derivatives of treatments that were originally discovered by accident. None were developed based on a scientific understanding of the causes or pathophysiology of mental illness.
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