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Nature Medicine 13, 1021 - 1023 (2007)
doi:10.1038/nm0907-1021
A skeleton key to metabolism
T John Martin1
- T. John Martin is in St. Vincent's Institute and the Department of Medicine, University of Melbourne, 9 Princes Street, Fitzroy 3065, Victoria, Australia. e-mail: jmartin@svi.edu.au
Abstract
The bone-specific protein osteocalcin has now been shown to act as a hormone that profoundly affects glucose and fat metabolism. This discovery completes an endocrine circuit with the skeleton as a ductless gland.
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