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Nature Medicine 13, 1015 - 1016 (2007)
doi:10.1038/nm0907-1015

The clot thickens—oxidized lipids and thrombosis

Shaun P Jackson1 & Anna C Calkin2

  1. Shaun P. Jackson is at the Australian Centre for Blood Diseases, Monash University, Melbourne, Australia. e-mail: shaun.jackson@med.monash.edu.au
  2. Anna C. Calkin is at the Baker Heart Research Institute, Alfred Medical Research & Education Precinct, Melbourne, Australia. e-mail: anna.calkin@baker.edu.au

Oxidized products of low-density lipoproteins (LDLs) activate platelets through CD36, demonstrating a link between deregulated lipoprotein levels, oxidative stress and thrombosis (pages 1086–1095).

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