Figures and tables index

From the following article

Essential role of stromally induced hedgehog signaling in B-cell malignancies

Christine Dierks, Jovana Grbic, Katja Zirlik, Ronak Beigi, Nathan P Englund, Gui-Rong Guo, Hendrik Veelken, Monika Engelhardt, Roland Mertelsmann, Joseph F Kelleher, Peter Schultz & Markus Warmuth

Nature Medicine 13, 944 - 951 (2007) Published online: 15 July 2007

doi:10.1038/nm1614

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Figure 1 - Unfortunately we are unable to provide accessible alternative text for this. If you require assistance to access this image, or to obtain a text description, please contact npg@nature.com

Figure 1

Hedgehog ligands provided by stromal cells from lymphoid organs are survival factors for lymphoma and multiple myeloma cells.

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Figure 2

Hh pathway inhibition induces apoptosis in stroma-dependent lymphoma cells.

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Figure 3

Constitutive Hh pathway activation in Myc-lymphoma cells induces highly proliferative lymphomas in the skin.

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Figure 4

Overexpression of hedgehog pathway members Fused and Gli1 or Bcl2, but not loss of the Cdkn2a-Arf locus, can inhibit cyclopamine-induced apoptosis in Myc-lymphomas.

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Figure 5

Hedgehog pathway inhibition abrogates lymphoma expansion in vivo.

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Table 1

Myc-lymphomas: phenotype and cyclopamine response

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