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Nature Medicine 13, 903 - 904 (2007)
doi:10.1038/nm0807-903
The curiosity of IL-15
Peter A Ward1
- Peter A. Ward is in the Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA. e-mail: pward@umich.edu
Abstract
Mice deficient for the cytokine interleukin-15 are unexpectedly protected from sepsis. Orinska and colleagues show that interleukin-15 signals intracellularly in mast cells and limits their recruitment of neutrophils to clear the infection (pages 927–934).
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