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Nature Medicine 13, 781 - 783 (2007)
doi:10.1038/nm0707-781
Stress, diet and abdominal obesity: Y?
James P Warne1 & Mary F Dallman1
- James P. Warne and Mary F. Dallman are in the Department of Physiology, University of California San Francisco, San Francisco, California 94143, USA. e-mail: mary.dallman@ucsf.edu
Abstract
In response to intense stress, neuropeptide Y facilitates all of the processes that result in adipose tissue growth, but only when mice are fed a palatable high-fat diet (pages 803–811).
In the current climate of epidemic obesity, understanding the mechanistic relationships between chronic stress and obesity1 becomes more urgent than ever. Chronic stressors exert many effects, including increased glucocorticoid secretion and persistently elevated signaling from the sympathetic nervous system.
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