News and Views
Nature Medicine 13, 784 - 786 (2007)
doi:10.1038/nm0707-784
Phosphoinositides' link to neurodegeneration
Laura Volpicelli-Daley1 & Pietro De Camilli1
- Laura Volpicelli-Daley and Pietro De Camilli are in the Department of Cell Biology, Howard Hughes Medical Institute and Program in Cellular Neuroscience, Neurodegeneration and Repair, Yale University School of Medicine, Boyer Center for Molecular Medicine, 295 Congress Avenue, New Haven, Connecticut 06510, USA. e-mail: pietro.decamilli@yale.edu
Abstract
Mutations in the phosphoinositide metabolism gene FIG4 disrupt the endosomal pathway, leading to neurodegeneration and a newly identified variant of Charcot-Marie-Tooth disorder.
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated.
RESEARCH
Mutation of FIG4 causes neurodegeneration in the pale tremor mouse and patients with CMT4JNature Letters to Editor (05 Jul 2007)
VAC14 nucleates a protein complex essential for the acute interconversion of PI3P and PI(3,5)P 2 in yeast and mouseThe EMBO Journal Article (17 Dec 2008)
VAC14 nucleates a protein complex essential for the acute interconversion of PI3P and PI(3,5)P 2 in yeast and mouseThe EMBO Journal Article
See all 5 matches for Research
