In a new role for an ion transporter, Na+-K+-Cl− cotransporter-1 may regulate the lung endothelial and epithelial barriers and consequently modulate the host response to pneumonia and sepsis.
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References
Ware, L.B. & Matthay, M.A. N. Engl. J. Med. 342, 1334–1349 (2000).
Rubenfeld, G.D. et al. N. Engl. J. Med. 353, 1685–1693 (2005).
Russell, J.A. et al. N. Engl. J. Med. 355, 1699–1713 (2006).
Nguyen, M. et al. J. Exp. Med. 204, 1383–1393 (2007).
Topper, J.N. et al. J. Clin. Invest. 99, 2941–2949 (1997).
O'Donnell, M.E. et al. J. Cereb. Blood Flow Metab. 24, 1046–1056 (2004).
Andrade, L. et al. Am. J. Physiol. Renal Physiol. 292, F586–F592 (2007).
Safdar, Z. et al. J. Clin. Invest. 112, 1541–1549 (2003).
Martin, T.R. et al. J. Clin. Invest. 84, 1609–1619 (1989).
Painter, R.G. et al. Biochemistry 45, 10260–10269 (2006).
Su, X. et al. FASEB. 21, A551 (2007).
Acute Respiratory Distress Syndrome Network. N. Engl. J. Med. 354, 2564–2575 (2006).
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Matthay, M., Su, X. Pulmonary barriers to pneumonia and sepsis. Nat Med 13, 780–781 (2007). https://doi.org/10.1038/nm0707-780
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DOI: https://doi.org/10.1038/nm0707-780
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