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Nature Medicine 13, 673 - 674 (2007)
doi:10.1038/nm0607-673
The hydrogen highway to reperfusion therapy
Katherine C Wood1 & Mark T Gladwin1
- The authors are at the Vascular Medicine Branch, Intramural Research Division, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland 20892, USA. e-mail: mgladwin@mail.nih.gov
Abstract
Hydrogen gas debuts as a selective antioxidant with explosive potential as cytoprotective therapy for ischemia-reperfusion injury and stroke.
Just when we thought we had exhausted our tool kit of therapeutic gases, Ohsawa et al.1 provide evidence that inhaled hydrogen gas (H2) has antioxidant and antiapoptotic activities that protect the brain against ischemia-reperfusion injury and stroke1.During the ischemic phase of thromboembolic stroke, a blood clot travels to and lodges in the distal blood vessels in the brain, blocking blood flow to the oxygen-starved tissue for a period of hours.
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RESEARCH
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicalsNature Medicine Article (01 Jun 2007)
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicalsNature Medicine Article
