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Nature Medicine 13, 532 - 534 (2007)
doi:10.1038/nm0507-532
The popcorn plaques
Jagat Narula1 & H William Strauss2
- Jagat Narula is at the University of California Irvine School of Medicine, Irvine, California 92705, USA. e-mail: narula@uci.edu
- H. William Strauss is at the Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA.
Abstract
Imaging of inflammation in atherosclerotic lesions may identify plaques vulnerable to rupture, and lead to better assessment of individuals at risk for acute coronary events such as myocardial infarction (pages 636–641).
Two-thirds of acute coronary events, such as myocardial infarction, unstable angina and sudden death, result from the rupture of atherosclerotic plaques in coronary arteries1. When these plaques pop open, their thrombogenic interior is exposed to the luminal blood, leading to clot formation and the acute event.
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