Access
To read this story in full you will need to login or make a payment (see right).
News and Views
Nature Medicine 13, 408 - 409 (2007)
doi:10.1038/nm0407-408
Immune cells may fend off Alzheimer disease
Markus Britschgi1 & Tony Wyss-Coray1,2
- Markus Britschgi and Tony Wyss-Coray are in the Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California 94305, USA.
- Tony Wyss-Coray is also at the Geriatric Research, Education and Clinical Center, Veterans Affairs Palo Alto Health Care System, Palo Alto, California 94304, USA. e-mail: twc@stanford.edu
Abstract
Chemokines in the brain recruit immune cells from the blood or from within the brain. Disrupting this line of communication exacerbates disease in mouse models of Alzheimer disease (pages 432–438).
The immune system and the central nervous system (CNS) are arguably the most complex organs, and, in the past, relatively few scientists have attempted to study their interactions. This is in part because the CNS was considered immune privileged and hands-off to the immune system except for a few autoimmune and infectious diseases.
To read this story in full you will need to login or make a payment (see right).
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated.
NEWS AND VIEWS
Immune cells may fend off Alzheimer diseaseNature Medicine News and Views (01 Apr 2007)
Inflammation takes on Alzheimer diseaseNature Medicine News and Views (01 Sep 2002)
See all 7 matches for News And ViewsRESEARCH
Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like diseaseNature Medicine Article (01 Apr 2007)
Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like diseaseNature Medicine Article (01 Apr 2007)
See all 12 matches for Research