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The ABCs of β-cell dysfunction in type 2 diabetes

Nature Medicine volume 13, pages 241–242 (2007)Cite this article

Cholesterol toxicity may damage pancreatic β-cells, leading to decreased insulin secretion and impaired glucose tolerance (pages 340–347).

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Figure 1: Pathways involved in insulin secretion in pancreatic β-cells.

Katie Ris

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Authors and Affiliations

  1. Division of Endocrinology, Metabolism and Lipid Research, Washington University School of Medicine, St. Louis, 63110, Missouri, USA

    Manu V Chakravarthy & Clay F Semenkovich

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  1. Manu V Chakravarthy
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  2. Clay F Semenkovich
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Chakravarthy, M., Semenkovich, C. The ABCs of β-cell dysfunction in type 2 diabetes. Nat Med 13, 241–242 (2007). https://doi.org/10.1038/nm0307-241

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