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Langerhans cells lap up HIV-1

Langerhans cells in the skin and mucosa have been thought to mediate the spread of HIV-1 in the body during sexual transmission. Instead, it seems that the cells protect against the virus, a finding with implications for the development of microbicides (pages 367–371).

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Figure 1: At the ready.

C Dezutter-Dambuyant/SG McCoombe & RV Short, AIDS

Figure 2: HIV-1 clearance by Langerhans cells.

Katie Ris

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Schwartz, O. Langerhans cells lap up HIV-1. Nat Med 13, 245–246 (2007). https://doi.org/10.1038/nm0307-245

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