1. Olivier Schwartz is in the Groupe Virus et Immunité, Centre National de la Recherche Scientifique (CNRS), URA3015, Institut Pasteur, Paris, 75015 France. e-mail: schwartz@pasteur.fr

Abstract

Langerhans cells in the skin and mucosa have been thought to mediate the spread of HIV-1 in the body during sexual transmission. Instead, it seems that the cells protect against the virus, a finding with implications for the development of microbicides (pages 367–371).

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