1. The authors are in the Research Division of the Hospital for Special Surgery, Weill College of Medicine of Cornell University, Caspary Research Building, 535 East 70th Street, New York, New York 10021, USA. e-mail: goldringm@hss.edu

Abstract

An inhibitor of the Wnt signaling pathway mediates bone destruction in inflammatory arthritis. The inhibitor may be the key to understanding why in some joint diseases bone is destroyed and in others built up (pages 156–163).

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