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Nature Medicine 13, 1405 - 1406 (2007)
doi:10.1038/nm1207-1405

Poring over pores: alpha-hemolysin and Panton-Valentine leukocidin in Staphylococcus aureus pneumonia

Juliane Bubeck Wardenburg1,2, Taeok Bae3, Michael Otto4, Frank R DeLeo4 & Olaf Schneewind1

  1. Departments of Microbiology, University of Chicago, Chicago, Illinois 60637, USA.
  2. Pediatrics, University of Chicago, Chicago, Illinois 60637, USA.
  3. Department of Microbiology and Immunology, Indiana University School of Medicine Northwest, Gary, Indiana 46408, USA.
  4. Laboratory of Human Bacterial Pathogenesis, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana 59840, USA. e-mail: oschnee@bsd.uchicago.edu

S. aureus pneumonia causes mortality in healthy individuals or hospital settings1, and recent increases in morbidity are attributed to the rapid spread of community-associated, methicillin-resistant strains (CA-MRSA)2, 3.

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