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Nature Medicine 13, 1417 - 1418 (2007)
doi:10.1038/nm1207-1417

Incapacitating the immune system in cystic fibrosis

Ian Sabroe1 & Moira K B Whyte1

  1. Ian Sabroe and Moira K.B. Whyte are in the Academic Unit of Respiratory Medicine, School of Medicine and Biomedical Sciences, University of Sheffield, Sheffield S10 2JF, UK. e-mail: i.sabroe@sheffield.ac.uk


Phagocytes swarm to the lung in individuals with cystic fibrosis but are unable to clear infection. A close examination of neutrophil biology reveals that Pseudomonas aeruginosa in the lung disables these phagocytes, which then turn on each other (pages 1423–1430).

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Incapacitating the immune system in cystic fibrosis

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