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Nature Medicine 13, 1284 - 1285 (2007)
doi:10.1038/nm1107-1284
Preventing kidney cell suicide
Michael Brownlee1
- Michael Brownlee is Director of the Juvenile Diabetes Research Foundation International Center for Diabetic Complications Research, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York 10461, USA. e-mail: Brownlee@aecom.yu.edu
Abstract
Decreased levels of activated protein C allow for kidney cell death in a mouse model of diabetic nephropathy. The findings suggest that targeting the antiapoptotic protein C pathway could counteract kidney damage in individuals with diabetes (pages 1349–1358).
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