News and Views


Nature Medicine 13, 1282 - 1284 (2007)
doi:10.1038/nm1107-1282

Blocking HDACs boosts regulatory T cells

Pavan Reddy1 & Weiping Zou1

  1. Pavan Reddy is in the Department of Internal Medicine and Weiping Zou is in the Department of Surgery, University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan 48109, USA e-mail: reddypr@umich.edu


Histone deacetylase inhibitors, which are in clinical use as anticancer agents, also affect the biology of regulatory T cells. These inhibitors may also hold promise as immunomodulatory drugs (pages 1299–1307).

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