News and Views
Nature Medicine 13, 1282 - 1284 (2007)
doi:10.1038/nm1107-1282
Blocking HDACs boosts regulatory T cells
- Pavan Reddy is in the Department of Internal Medicine and Weiping Zou is in the Department of Surgery, University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan 48109, USA e-mail: reddypr@umich.edu
Abstract
Histone deacetylase inhibitors, which are in clinical use as anticancer agents, also affect the biology of regulatory T cells. These inhibitors may also hold promise as immunomodulatory drugs (pages 1299–1307).
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