Ticket scalpers - p1121

doi:10.1038/nm1007-1121

Abstract - | Full Text - Ticket scalpers | PDF (87 KB) - Ticket scalpers

Amidst doubts, space research program takes flight - p1123

Emma Marris

doi:10.1038/nm1007-1123

Full Text - Amidst doubts, space research program takes flight | PDF (254 KB) - Amidst doubts, space research program takes flight

Poor trial design leaves gene therapy death a mystery - p1124

Meredith Wadman

doi:10.1038/nm1007-1124a

Full Text - Poor trial design leaves gene therapy death a mystery | PDF (131 KB) - Poor trial design leaves gene therapy death a mystery

Karolinska Institute under fire for controversial cancer report - p1124

Cassandra Willyard

doi:10.1038/nm1007-1124b

Full Text - Karolinska Institute under fire for controversial cancer report | PDF (131 KB) - Karolinska Institute under fire for controversial cancer report

Straight talk from... Colin Blakemore - p1125

Michael Hopkin

doi:10.1038/nm1007-1125

Abstract - | Full Text - Straight talk from... Colin Blakemore | PDF (125 KB) - Straight talk from... Colin Blakemore

News in brief - pp1126 - 1127

doi:10.1038/nm1007-1126

Abstract - | Full Text - News in brief | PDF (432 KB) - News in brief

Reply to 'UK set to reverse stance on research with chimeras' - p1133

Richard Hynes

doi:10.1038/nm1007-1133

Full Text - Reply to 'UK set to reverse stance on research with chimeras' | PDF (58 KB) - Reply to 'UK set to reverse stance on research with chimeras'

Taking a chance - p1135

Jutta Schickore reviews Happy Accidents: Serendipity in Modern Medical Breakthroughs by Morton A. Meyers

doi:10.1038/nm1007-1135

Full Text - Taking a chance | PDF (83 KB) - Taking a chance

It's what you do with the fat that matters! - pp1137 - 1138

Clinton R Bruce & Mark A Febbraio

doi:10.1038/nm1007-1137

Abstract - | Full Text - It's what you do with the fat that matters! | PDF (292 KB) - It's what you do with the fat that matters!

See also: Article by Matsuzaka et al.

Keeping quiet: microRNAs in HIV-1 latency - pp1138 - 1140

Yefei Han & Robert F Siliciano

doi:10.1038/nm1007-1138

Abstract - | Full Text - Keeping quiet: microRNAs in HIV-1 latency | PDF (209 KB) - Keeping quiet: microRNAs in HIV-1 latency

See also: Letter by Huang et al.

Merging mitochondria for neuronal survival - pp1140 - 1141

Giovanni Manfredi & M Flint Beal

doi:10.1038/nm1007-1140

Abstract - | Full Text - Merging mitochondria for neuronal survival | PDF (444 KB) - Merging mitochondria for neuronal survival

Rechallenging immunological memory - p1142

Kate Jeffrey

doi:10.1038/nm1007-1142a

Full Text - Rechallenging immunological memory | PDF (113 KB) - Rechallenging immunological memory

See also: Letter by Dong Kim et al.

Not so fast: adaptive suppression of innate immunity - pp1142 - 1144

Noah W Palm & Ruslan Medzhitov

doi:10.1038/nm1007-1142b

Abstract - | Full Text - Not so fast: adaptive suppression of innate immunity | PDF (262 KB) - Not so fast: adaptive suppression of innate immunity

See also: Letter by Dong Kim et al.

Where lies the blame for resistance—tumor or host? - pp1144 - 1145

Charles L Sawyers

doi:10.1038/nm1007-1144

Abstract - | Full Text - Where lies the blame for resistance—tumor or host? | PDF (310 KB) - Where lies the blame for resistance—tumor or host?

The phantom menace? - p1146

Katherine Stevens

doi:10.1038/nm1007-1146a

Full Text - The phantom menace? | PDF (161 KB) - The phantom menace?

'Multipurpose oxidase' in atherogenesis - pp1146 - 1147

Daniel J Rader & Harry Ischiropoulos

doi:10.1038/nm1007-1146b

Abstract - | Full Text - 'Multipurpose oxidase' in atherogenesis | PDF (516 KB) - 'Multipurpose oxidase' in atherogenesis

See also: Article by Wang et al.

Research Highlights - p1149

doi:10.1038/nm1007-1149

Full Text - Research Highlights | PDF (114 KB) - Research Highlights

2007 Albert Lasker Medical Research Awards

Creation and revelation: two different routes to advancement in the biomedical sciences - pp1151 - 1154

Joseph L Goldstein

doi:10.1038/nm1642

Full Text - Creation and revelation: two different routes to advancement in the biomedical sciences | PDF (537 KB) - Creation and revelation: two different routes to advancement in the biomedical sciences

2007 Albert Lasker Medical Research Awards

Dendritic cells: versatile controllers of the immune system - pp1155 - 1159

Ralph M Steinman

doi:10.1038/nm1643

Full Text - Dendritic cells: versatile controllers of the immune system | PDF (671 KB) - Dendritic cells: versatile controllers of the immune system

2007 Albert Lasker Medical Research Awards

The artificial heart valve - pp1160 - 1164

Albert Starr

doi:10.1038/nm1644

Full Text - The artificial heart valve | PDF (895 KB) - The artificial heart valve

2007 Albert Lasker Medical Research Awards

The surprising rise of nonthrombogenic valvular surgery - pp1165 - 1168

Alain Carpentier

doi:10.1038/nm1645

Full Text - The surprising rise of nonthrombogenic valvular surgery | PDF (569 KB) - The surprising rise of nonthrombogenic valvular surgery

2007 Albert Lasker Medical Research Awards

The expanding global health agenda: a welcome development - pp1169 - 1171

Anthony S Fauci

doi:10.1038/nm1646

Full Text - The expanding global health agenda: a welcome development | PDF (410 KB) - The expanding global health agenda: a welcome development

Human T_H17 lymphocytes promote blood-brain barrier disruption and central nervous system inflammation - pp1173 - 1175

Hania Kebir, Katharina Kreymborg, Igal Ifergan, Aurore Dodelet-Devillers, Romain Cayrol, Monique Bernard, Fabrizio Giuliani, Nathalie Arbour, Burkhard Becher & Alexandre Prat

doi:10.1038/nm1651

Abstract - | Full Text - Human TH17 lymphocytes promote blood-brain barrier disruption and central nervous system inflammation | PDF (350 KB) - Human TH17 lymphocytes promote blood-brain barrier disruption and central nervous system inflammation | Supplementary information

Protein carbamylation links inflammation, smoking, uremia and atherogenesis - pp1176 - 1184

Zeneng Wang, Stephen J Nicholls, E Rene Rodriguez, Outi Kummu, Sohvi Hörkkö, John Barnard, Wanda F Reynolds, Eric J Topol, Joseph A DiDonato & Stanley L Hazen

doi:10.1038/nm1637

Abstract - | Full Text - Protein carbamylation links inflammation, smoking, uremia and atherogenesis | PDF (438 KB) - Protein carbamylation links inflammation, smoking, uremia and atherogenesis | Supplementary information

27-Hydroxycholesterol is an endogenous SERM that inhibits the cardiovascular effects of estrogen - pp1185 - 1192

Michihisa Umetani, Hideharu Domoto, Andrew K Gormley, Ivan S Yuhanna, Carolyn L Cummins, Norman B Javitt, Kenneth S Korach, Philip W Shaul & David J Mangelsdorf

doi:10.1038/nm1641

Abstract - | Full Text - 27-Hydroxycholesterol is an endogenous SERM that inhibits the cardiovascular effects of estrogen | PDF (387 KB) - 27-Hydroxycholesterol is an endogenous SERM that inhibits the cardiovascular effects of estrogen | Supplementary information

Crucial role of a long-chain fatty acid elongase, Elovl6, in obesity-induced insulin resistance - pp1193 - 1202

Takashi Matsuzaka, Hitoshi Shimano, Naoya Yahagi, Toyonori Kato, Ayaka Atsumi, Takashi Yamamoto, Noriyuki Inoue, Mayumi Ishikawa, Sumiyo Okada, Naomi Ishigaki, Hitoshi Iwasaki, Yuko Iwasaki, Tadayoshi Karasawa, Shin Kumadaki, Toshiyuki Matsui, Motohiro Sekiya, Ken Ohashi, Alyssa H Hasty, Yoshimi Nakagawa, Akimitsu Takahashi, Hiroaki Suzuki, Sigeru Yatoh, Hirohito Sone, Hideo Toyoshima, Jun-ichi Osuga & Nobuhiro Yamada

doi:10.1038/nm1662

Abstract - | Full Text - Crucial role of a long-chain fatty acid elongase, Elovl6, in obesity-induced insulin resistance | PDF (482 KB) - Crucial role of a long-chain fatty acid elongase, Elovl6, in obesity-induced insulin resistance | Supplementary information

Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia - pp1203 - 1210

Teresa Palomero, Maria Luisa Sulis, Maria Cortina, Pedro J Real, Kelly Barnes, Maria Ciofani, Esther Caparros, Jean Buteau, Kristy Brown, Sherrie L Perkins, Govind Bhagat, Archana M Agarwal, Giuseppe Basso, Mireia Castillo, Satoru Nagase, Carlos Cordon-Cardo, Ramon Parsons, Juan Carlos Zúñiga-Pflücker, Maria Dominguez & Adolfo A Ferrando

doi:10.1038/nm1636

Abstract - | Full Text - Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia | PDF (405 KB) - Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia | Supplementary information

Mast cells are required for angiogenesis and macroscopic expansion of Myc-induced pancreatic islet tumors - pp1211 - 1218

Laura Soucek, Elizabeth R Lawlor, Darya Soto, Ksenya Shchors, Lamorna Brown Swigart & Gerard I Evan

doi:10.1038/nm1649

Abstract - | Full Text - Mast cells are required for angiogenesis and macroscopic expansion of Myc-induced pancreatic islet tumors | PDF (1,028 KB) - Mast cells are required for angiogenesis and macroscopic expansion of Myc-induced pancreatic islet tumors | Supplementary information

Identification of tendon stem/progenitor cells and the role of the extracellular matrix in their niche - pp1219 - 1227

Yanming Bi, Driss Ehirchiou, Tina M Kilts, Colette A Inkson, Mildred C Embree, Wataru Sonoyama, Li Li, Arabella I Leet, Byoung-Moo Seo, Li Zhang, Songtao Shi & Marian F Young

doi:10.1038/nm1630

Abstract - | Full Text - Identification of tendon stem/progenitor cells and the role of the extracellular matrix in their niche | PDF (1,199 KB) - Identification of tendon stem/progenitor cells and the role of the extracellular matrix in their niche | Supplementary information

LINGO-1 antagonist promotes spinal cord remyelination and axonal integrity in MOG-induced experimental autoimmune encephalomyelitis - pp1228 - 1233

Sha Mi, Bing Hu, Kyungmin Hahm, Yi Luo, Edward Sai Kam Hui, Qiuju Yuan, Wai Man Wong, Li Wang, Huanxing Su, Tak-Ho Chu, Jiasong Guo, Wenming Zhang, Kwok-Fai So, Blake Pepinsky, Zhaohui Shao, Christilyn Graff, Ellen Garber, Vincent Jung, Ed Xuekui Wu & Wutian Wu

doi:10.1038/nm1664

Abstract - | Full Text - LINGO-1 antagonist promotes spinal cord remyelination and axonal integrity in MOG-induced experimental autoimmune encephalomyelitis | PDF (890 KB) - LINGO-1 antagonist promotes spinal cord remyelination and axonal integrity in MOG-induced experimental autoimmune encephalomyelitis | Supplementary information

Central control of bone remodeling by neuromedin U - pp1234 - 1240

Shingo Sato, Reiko Hanada, Ayako Kimura, Tomomi Abe, Takahiro Matsumoto, Makiko Iwasaki, Hiroyuki Inose, Takanori Ida, Michihiro Mieda, Yasuhiro Takeuchi, Seiji Fukumoto, Toshiro Fujita, Shigeaki Kato, Kenji Kangawa, Masayasu Kojima, Ken-ichi Shinomiya & Shu Takeda

doi:10.1038/nm1640

First paragraph - | Full Text - Central control of bone remodeling by neuromedin U | PDF (618 KB) - Central control of bone remodeling by neuromedin U | Supplementary information

Cellular microRNAs contribute to HIV-1 latency in resting primary CD4⁺ T lymphocytes - pp1241 - 1247

Jialing Huang, Fengxiang Wang, Elias Argyris, Keyang Chen, Zhihui Liang, Heng Tian, Wenlin Huang, Kathleen Squires, Gwen Verlinghieri & Hui Zhang

doi:10.1038/nm1639

First paragraph - | Full Text - Cellular microRNAs contribute to HIV-1 latency in resting primary CD4+ T lymphocytes | PDF (331 KB) - Cellular microRNAs contribute to HIV-1 latency in resting primary CD4+ T lymphocytes | Supplementary information

Adaptive immune cells temper initial innate responses - pp1248 - 1252

Kwang Dong Kim, Jie Zhao, Sogyong Auh, Xuanming Yang, Peishuang Du, Hong Tang & Yang-Xin Fu

doi:10.1038/nm1633

First paragraph - | Full Text - Adaptive immune cells temper initial innate responses | PDF (252 KB) - Adaptive immune cells temper initial innate responses | Supplementary information

In vivo magnetic resonance imaging of acute brain inflammation using microparticles of iron oxide - pp1253 - 1258

Martina A McAteer, Nicola R Sibson, Constantin von zur Muhlen, Jurgen E Schneider, Andrew S Lowe, Nicholas Warrick, Keith M Channon, Daniel C Anthony & Robin P Choudhury

doi:10.1038/nm1631

First paragraph - | Full Text - In vivo magnetic resonance imaging of acute brain inflammation using microparticles of iron oxide | PDF (423 KB) - In vivo magnetic resonance imaging of acute brain inflammation using microparticles of iron oxide | Supplementary information

Catching bird flu in a droplet - pp1259 - 1263

Juergen Pipper, Masafumi Inoue, Lisa F-P Ng, Pavel Neuzil, Yi Zhang & Lukas Novak

doi:10.1038/nm1634

First paragraph - | Full Text - Catching bird flu in a droplet | PDF (273 KB) - Catching bird flu in a droplet | Supplementary information

Corrigenda: Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: a randomized Phase 2 clinical trial - p1264

Sandeep T Patil, Lu Zhang, Ferenc Martenyi, Stephen L Lowe, Kimberley A Jackson, Boris V Andreev, Alla S Avedisova, Leonid M Bardenstein, Issak Y Gurovich, Margarita A Morozova, Sergey N Mosolov, Nikolai G Neznanov, Alexander M Reznik, Anatoly B Smulevich, Vladimir A Tochilov, Bryan G Johnson, James A Monn & Darryle D Schoepp

doi:10.1038/nm1007-1264

Full Text - Corrigenda: Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: a randomized Phase 2 clinical trial | PDF (47 KB) - Corrigenda: Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: a randomized Phase 2 clinical trial