Figures and tables index
From the following article
27-Hydroxycholesterol is an endogenous SERM that inhibits the cardiovascular effects of estrogen
Michihisa Umetani, Hideharu Domoto, Andrew K Gormley, Ivan S Yuhanna, Carolyn L Cummins, Norman B Javitt, Kenneth S Korach, Philip W Shaul & David J Mangelsdorf
Nature Medicine 13, 1185 - 1192 (2007) Published online: 16 September 2007
doi:10.1038/nm1641
Figure 2
27HC inhibits the actions of E2 on NO production in vascular cells.
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27HC decreases vascular NOS expression in an ER-dependent manner.
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27HC Inhibits nontranscriptional effects of E2 on NOS enzyme activity in vascular cells.
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27HC inhibits E2-induced endothelial cell migration and reendothelialization in mice.
Full size figure and legend (91 KB)Figure 6
Model of 27HC inhibition of the vasoprotective effects of estrogen.
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