Figures and tables index
From the following article
Protein carbamylation links inflammation, smoking, uremia and atherogenesis
Zeneng Wang, Stephen J Nicholls, E Rene Rodriguez, Outi Kummu, Sohvi Hörkkö, John Barnard, Wanda F Reynolds, Eric J Topol, Joseph A DiDonato & Stanley L Hazen
Nature Medicine 13, 1176 - 1184 (2007) Published online: 9 September 2007
doi:10.1038/nm1637
Figure 1
Schematic illustration of pathways for promoting protein carbamylation and their link to atherosclerosis.
Full size figure and legend (39 KB)Figure 2
Production of OCN- and homocitrulline (HCit) in the reaction of proteins with MPO/SCN-/H2O2.
Full size figure and legend (81 KB)Figure 3
MPO is a catalytic source for carbamylation at sites of inflammation and within human atherosclerotic plaque.
Full size figure and legend (95 KB)Figure 4
Potential pro-atherogenic effects of MPO-catalyzed protein carbamylation.
Full size figure and legend (96 KB)Figure 5
Case/control study examining the relationship between plasma concentrations of protein-bound HCit and the prevalence of atherosclerotic CVD.
Full size figure and legend (71 KB)Figure 6
Case/control study examining the relationship between plasma abundance of protein-bound HCit and prospective risk for major adverse cardiac event (MACE; one or more of the following conditions: nonfatal MI, stroke, need for revascularization (Revasc.) or death).
Full size figure and legend (84 KB)