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Correspondence
Nature Medicine 13, 18 - 19 (2007)
doi:10.1038/nm0107-18
Is leptin an important physiological regulator of CRP?
Arieh Gertler1, Leonora Niv-Spector1 & Shay Reicher1
- Faculty of Agricultural, Food and Environmental Quality Sciences, Hebrew University, Rehovot 76100, Israel. e-mail: gertler@agri.huji.ac.il
Interaction of human leptin (hLEP) with human C-reactive protein (hCRP) was recently suggested as one of the major reasons for leptin resistance1. This notion is interesting because, if correct, preparation of leptin mutants that do not interact with CRP but retain their ability to interact and activate leptin receptors (LEPRs) would give us a potent biopharmaceutical reagent that could overcome such resistance.
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RESEARCH
Is leptin an important physiological regulator of CRP?Nature Medicine Correspondence (01 Jan 2007)
