News and Views


Nature Medicine 13, 31 - 32 (2007)
doi:10.1038/nm0107-31

Bad signals jam organelle traffic

Esteban C Dell'Angelica1

  1. The author is in the Department of Human Genetics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California 90095, USA. e-mail: edellangelica@mednet.ucla.edu


Defects in organelle biogenesis and trafficking underlie a newly described genetic disorder. These defects are traced to the gene encoding a scaffolding protein that coordinates signal transduction events on late endosomes (pages 3845).

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