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Taming the clot-buster tPA

Treating stroke with tissue plasminogen activator (tPA) can help dissolve blood clots and improve outcome. But tPA also increases the risk of hemorrhage and has other deleterious effects. A new approach to treatment minimizes these negative effects.

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Figure 1: Counteracting a clot.

Kim Caesar

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Dawson, T., Dawson, V. Taming the clot-buster tPA. Nat Med 12, 993–994 (2006). https://doi.org/10.1038/nm0906-993

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