Circulating natural killer cells might be best known for their ability to disable and maim target cells. But in the pregnant uterus of humans these cells seem to have a positive effect, regulating placental development and angiogenesis (pages 1065–1074).
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Trophoblast-derived CXCL16 induces M2 macrophage polarization that in turn inactivates NK cells at the maternal–fetal interface
Cellular & Molecular Immunology Open Access 27 March 2018
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Le Bouteiller, P., Tabiasco, J. Killers become builders during pregnancy. Nat Med 12, 991–992 (2006). https://doi.org/10.1038/nm0906-991
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DOI: https://doi.org/10.1038/nm0906-991
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