Nature Medicine
- 12, 925 - 932 (2006)
Published online: 30 July 2006; | doi:10.1038/nm1448
Embryonic and tumorigenic pathways converge via Nodal signaling: role in melanoma aggressivenessJolanta M Topczewska, Lynne-Marie Postovit, Naira V Margaryan, Anthony Sam, Angela R Hess, William W Wheaton, Brian J Nickoloff, Jacek Topczewski & Mary J C Hendrix Supplementary Fig. 1 (pdf 532K) Schematic representation of melanoma cell transplantation experiments. Supplementary Fig. 2 (pdf 2M) The overexpression of the lefty1 inhibits secondary axis formation induced by transplanted aggressive C8161 melanoma cells. Supplementary Fig. 3 (pdf 436K) Patterns of Nodal expression in primary and metastatic cutaneous melanoma and breast carcinoma cell lines. Supplementary Fig. 4 (pdf 892K) Nodal-mediated signaling and gene regulation in melanoma cells. Supplementary Fig. 5 (pdf 688K) TUNEL assay of melanoma cells treated with MONodal or SB431542. Supplementary Note (pdf 92K)
|